Polysaccharide

Cinnamaldehyde

(PSC)

Animal Gastrointestinal Protector,

Replacing Zinc Oxide and Antibiotics

Introduction

Polysaccharide Cinnamaldehyde, developed by Univet, is a safe and effective alternative to zinc oxide and antibiotics.

It binds to intestinal mucus, adheres to the mucosal surface, and reaches more than three times the concentration of traditional coated cinnamaldehyde. This effectively suppresses harmful microorganisms in the gut lining, controls diarrhea, and improves growth performance.

Polysaccharide Cinnamaldehyde is produced through the condensation of polysaccharide amino groups with cinnamaldehyde, forming C=N bonds. Its anti-diarrheal effect is 2.5 times stronger than zinc oxide and more than three times stronger than tannic acid. Polysaccharide binding reduces irritation while preserving the mucosal protection and repair functions of polysaccharide mucins.

Mechanism of Zinc Oxide–Induced Gastrointestinal Injury in the Weaning Period

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Polysaccharide–Cinnamaldehyde Versus High-Dose Zinc Oxide

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In Vitro Intestinal Mucus Dilution Experiment

Polysaccharide cinnamaldehyde shows stronger mucus binding and thickening than zinc oxide. While high-dose zinc oxide raises G′ to 180 Pa with high turbidity (OD600 = 0.80), polysaccharide cinnamaldehyde achieves 240 Pa at lower doses with good transparency (OD600 = 0.20). Its lower tan δ (0.45 vs. 0.65) indicates a more complete gel transition.

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Usage

Feed addition: Swine: 1–1.5 kg/T in zinc oxide–free nursery feed, or 0.5–1 kg/T when used with zinc oxide.

Clinical application:
· Swine: 1 kg/T of complete feed for piglets to control post-weaning stress and diarrhea, including PED and ASFV causes. Increases feed intake by more than 10%.
· Poultry: 200–400 g/T of complete feed to rapidly control stress, watery droppings, glandular gastritis, and diarrhea, improving feed-to-meat ratio by 0.05 in broilers.
· Aquaculture: 0.5–1 kg/T of complete feed to control intestinal mucosal shedding, stringy feces, and white feces.